PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS.
摘要
<p>The present invention describes a process for the synthesis of a semi-synthetic β-lactam compound from a nucleus and a side chain selected from the group consisting of D-phenylglycine and D-dihydro-phenylglycine in the form of a side chain ester and an enzyme catalyzing the coupling of the side chain ester to the nucleus characterized in that the side chain ester is not isolated as a solid intermediate.</p>
申请公布号
MX2009009526(A)
申请公布日期
2009.09.16
申请号
MX20090009526
申请日期
2008.03.10
申请人
DSM IP ASSETS B.V.
发明人
MOODY, HAROLD, MONRO;DOES, VAN DER, THOMAS;DOOREN, VAN, THEODORUS, JOHANNES, GODFRIED, MARIA