发明名称 |
CATIONIC LIPOSOME DELIVERY OF TAXANES TO ANGIOGENIC BLOOD VESSELS |
摘要 |
Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell. |
申请公布号 |
PL203128(B1) |
申请公布日期 |
2009.08.31 |
申请号 |
PL20000354721 |
申请日期 |
2000.09.08 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MCDONALD DONALD M.;MCLEAN JOHN W.;THURSTON GAVIN O. |
分类号 |
A61K9/127;A61K31/337;A61K47/24;A61P7/00;A61P9/10;A61P17/02;A61P29/00;A61P35/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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