发明名称 Complete human monoclonal IgG4lambda specific for CTLA-4 and uses thereof for detection of soluble CTLA-4 and isolation of regulatory cells
摘要 The present invention provides a CTLA-4 non-blocking agent of a complete human antibody nature, thus is non-immunogenic in a human. The immunoassay method using such a non-blocking agent measures the CTLA-4 content in a sample of a human subject. The present invention further provides a novel method for isolating human regulatory T cells. The resultant enriched and depleted cellular populations are useful in treating or ameliorating of human diseases.
申请公布号 US2009214553(A1) 申请公布日期 2009.08.27
申请号 US20070943682 申请日期 2007.11.21
申请人 CHIN LI-TE;HSU SHU-CHING 发明人 CHIN LI-TE;HSU SHU-CHING
分类号 A61K39/395;A61K35/26;C07K16/28;C12N5/02;C12N5/08;G01N33/566 主分类号 A61K39/395
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