发明名称 |
TUMOR THERAPY WITH REPLICATION COMPETENT SINDBIS VIRAL VECTORS |
摘要 |
Disclosed herein are methods for treating a mammal harboring a solid tumor which expresses higher levels of High Affinity Laminin Receptors (LAMR) than normal cells of the same lineage comprising systematically administering to a mammal in need of such treatment a therapeutically effective amount of a Replication Competent (RC) Sindbis virus vector, wherein said vector encodes a suicide gene.
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申请公布号 |
US2009214425(A1) |
申请公布日期 |
2009.08.27 |
申请号 |
US20090390096 |
申请日期 |
2009.02.20 |
申请人 |
NEW YORK UNIVERSITY |
发明人 |
MERUELO DANIEL;TSENG JEN-CHIEH |
分类号 |
A61K51/06;A61K31/7052;A61K49/00;A61P35/00;C12N15/63;C12Q1/68 |
主分类号 |
A61K51/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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