LIVER TOXICITY DISORDER COMPOSITION COMPRISING AN EXTRACT FROM THE SEED OF OPUNTIA FICUS-INDICA VAR. SABOTEN AND COMPOUNDS ISOLATED THEREFROM

摘要

A composition for preventing and treating hepatotoxic diseases, which contains Opuntia ficus-indica var. saboten seed extract or compound isolated from the extract is provided to have excellent liver protection effect and liver recovery effect in generation of hepatotoxicity. A composition for preventing and treating hepatotoxicity comprises an alcohol extract of Opuntia ficus-indica var. saboten seed as an active ingredient. A method for producing the alcohol extract of Opuntia ficus-indica var. saboten seed comprises: a step of adding 0.1-10 ‘± of alcohol solvent per 1kg of seed powder and performing reflux at 60-100‹C for two to six hours; and a step of filtering and compressing. The method further comprises a step of adding 1-5L of ethylacetate(EtOAc) to have fraction.