| 摘要 |
PROBLEM TO BE SOLVED: To provide a new medicine usable for treatment and prevention of arteriosclerosis, and having excellent safety. SOLUTION: The pulse wave propagation velocity (PWV) depressant is a composition containing at least one dipeptide selected from the group consisting of Val-Tyr, Val-Trp, Tyr-Trp and Ile-Tyr. The dipeptide can be prepared, for example, by treating lees of Sake (rice wine) with a protease. The increased PWV can be decreased by such the PWV depressant, and therefore the PWV depressant is useful as a treating agent of the arteriosclerosis or a preventive agent of the arteriosclerosis. COPYRIGHT: (C)2009,JPO&INPIT
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