| 发明名称 |
1,5-DIPENYL-3-BENZYLAMIN0-1,5-DIHYDR0PYRR0LIDIN-2-0NE AS CB1 RECEPTOR MODULATORS |
| 摘要 |
Compounds and pharmaceutical compositions of Formula by blockade of the CB1 receptors via an inverse agonism mechanism which are useful for reducing body weight in mammals, cognitive impairment associated with schizophrenia, mitigating treatment emergent weight gain observed during treatment with antipsychotics and have increased bioavailability.
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| 申请公布号 |
KR20090071613(A) |
申请公布日期 |
2009.07.01 |
| 申请号 |
KR20097008214 |
申请日期 |
2007.10.22 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
COFFEY DAVID SCOTT;HU JINGDAN;KEDING STACY JO;KRUSHINSKI JOSEPH HERMAN JUNIOR;SCHAUS JOHN MEHNERT;TUPPER DAVID EDWARD |
| 分类号 |
C07D401/12;A61K31/4025;A61P25/00;C07D213/38 |
主分类号 |
C07D401/12 |
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