发明名称 |
METHOD AND COMPOUNDS FOR MODULATING INSULIN PRODUCTION |
摘要 |
The present invention provides screening methods for the detection of agents that affect various aspects of beta-cell biology, particularly insulin gene expression. Screening methods are also provided for detection of agents that affect beta-cell differentiation from progenitor cells. Additionally, agents identified using such methods are provided and are useful for increasing insulin gene expression and reducing lipotoxicity.
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申请公布号 |
US2009137543(A1) |
申请公布日期 |
2009.05.28 |
申请号 |
US20080267507 |
申请日期 |
2008.11.07 |
申请人 |
LEVINE FRED;ITKIN-ANSARI PAMELA;MERCOLA MARK |
发明人 |
LEVINE FRED;ITKIN-ANSARI PAMELA;MERCOLA MARK |
分类号 |
A61K31/57;A61K31/015;A61K31/196;A61K31/5415;A61K31/56;C12Q1/02;C12Q1/26;C12Q1/34;C12Q1/48;C12Q1/66 |
主分类号 |
A61K31/57 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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