Humanized forms of an anti-CRIPTO antibody and portions thereof. In one embodiment, the variable regions of these antibodies or polypeptides comprising them (e.g., full-length antibodies or domain deleted antibodies) can be used to treat disorders, such as cancer.
申请公布号
ZA200706348(B)
申请公布日期
2009.05.27
申请号
ZA20070006348
申请日期
2007.07.31
申请人
BIOGEN IDEC MA INC.
发明人
GLASER, SCOTT;LUGOVSKOY, ALEXEY ALEXANDROVICH;WU, XIUFENG;SALDANHA, JOSE WILLIAM;VAN VLIJMEN, HERMAN;SANICOLA-NADEL, MICHELE;GARBER, ELLEN