| 摘要 |
<p>Disclosed is a sustained release composition containing SDF-1.Specifically disclosed is a sustained release composition which comprises (1) SDF-1 and (2) a hydrogel comprising a modified gelatin having a carboxyl group and/or a sulfo group. The composition can release SDF-1, which is a chemokine capable of accelerating the accumulation of a blood vessel progenitor cell in vivo, in a sustained manner. Therefore, the composition can be used as a pharmaceutical composition in various dosage forms, such as a therapeutic agent for an ischemic disease, a bone disease or the like and/or an inhibitor of the progression of conditions of the disease.</p> |
