发明名称 |
Polypeptide-Nucleic Acid Conjugate for Immunoprophylaxis or Immunotherapy for Neoplastic or Infectious Disorders |
摘要 |
The present invention discloses compositions which induce cross-activation of immune mediated and direct death signaling in targeted cells by exploiting the properties of a antibody/peptide-nucleic acid conjugate. The conjugate is able to simultaneously activate multiple death signaling mechanisms. Methods of using the conjugate of the present invention as an immunotherapeutic modality for the treatment or prevention of infectious disease, neoplastic diseases or other disorders. |
申请公布号 |
US2009123467(A1) |
申请公布日期 |
2009.05.14 |
申请号 |
US20080184246 |
申请日期 |
2008.07.31 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
BEDI ATUL;RAVI RAJANI;LI SHULIN |
分类号 |
A61K39/39;A61P37/02;C07K2/00;C07K16/00 |
主分类号 |
A61K39/39 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|