| 发明名称 |
PROCEDURE FOR THE CHROMATOGRAPHIC PURIFICATION OF INSULINS |
| 摘要 |
The invention relates to an improved method for chromatographically purifyin g insulins. The invention is characterized in that a pressure-stable, organic, and polymeric chromatographic material is used as a stationary phase, and in that the mobile phase contains at least one organic solvent which can be mixed with water, and contains at least one buffering agent. In addition, the invention is characterized in that the pH value ranges from 7 to 11.
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| 申请公布号 |
CA2341355(C) |
申请公布日期 |
2009.04.07 |
| 申请号 |
CA19992341355 |
申请日期 |
1999.08.11 |
| 申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
VON EYSMONDT, JORG;BICKER, RICHARD;SIEVERS, WERNER;KELLER, REINHOLD;RICHARD, FRANK;DESCH, DIETER |
| 分类号 |
C07K14/62;G01N30/88;A61K38/28;A61P3/10;B01D15/08;B01J20/281;B01J20/285;C07K1/14;C07K1/16;G01N30/26;G01N30/34 |
主分类号 |
C07K14/62 |
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