LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS

摘要

THE PRESENT APPLICATION DESCRIBES LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF OF FORMULA I ; IOR PHARMACEUTICALLY ACCEPTABLE SALTS FORMS THEREOF, WHEREIN RING P, IF PRESENT IS A 5-7 MEMBERED CARBOCYCLE OR HETEROCYCLE AND RING M IS A 5-7 MEMBERED CARBOCYCLE OR HETEROCYCLE. COMPOUNDS OF THE PRESENT INVENTION ARE USEFUL AS INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASES, SPECIFICALLY FACTOR Xa.