| 摘要 |
<p>There are provided compounds which can be used in the treatment of diseases mediated by the autophosphorylation of a PDGF receptor, specifically, compounds which can inhibit neointima formation hypertrophy. The compounds are those represented by formula (I) or pharmacologically acceptable salts or solvates thereof: <CHEM> wherein R<1> and R<2> represent hydrogen, alkyl or the like; R<3>, R<4>, R<5>, and R<6> represent hydrogen, halogen, alkyl, alkoxy or the like; R<11> and R<12> represent hydrogen, alkyl, alkylcarbonyl or the like; and A represents any one of formulae (i) to (x), provided that compounds wherein R<3>, R<4>, R<5> and R<6> represent hydrogen and A represents group (v) wherein u is 0 (zero) and R<19> represents phenyl optionally substituted by halogen, alkyl, or alkoxy are excluded.</p> |
