METHOD AND DISPOSABLE DEVICES FOR MICRO EXTRACTION

摘要

An apparatus for carrying out liquid-liquid mi-cro extraction or liquid-liquid-liquid micro extraction with high enrichment comprises: a) a container for a sample solution having volume Vs with dissolved substance, analyte, to be analysed, b) a second con-tainer arranged in the first container, preferably a dis-posable container, having permeable membrane walls, for an acceptor solution, having volume Va, wherein 1) Vs:Va .gtoreq. 50 and 2) about 1 .mu.l .ltoreq. Va .ltoreq. 50 .mu.l, c) stir-ring means, preferably a magnetic bar. The method is applicable for liquid-liquid micro extraction (LLME) and liquid-liquid-liquid micro extraction (LLLME) with high enrichment. In the latter case, a liquid im-miscible with the sample solution and the acceptor solution is immobilised in the wall of the container for the acceptor solution. There is also described a disposable device for use in liquid-liquid micro ex-traction in the form of a sponge body having defined pore volume for absorption of an immobilised accep-tor solution for an analyte from a volume of a sample solution.