发明名称 VOLTAGE-GATED ION CHANNEL MUTANTS FOR USE IN IDENTIFYING IONCHANNEL MODULATING COMPOUNDS
摘要 The present invention provides novel methods and compositions for identifying ion channel modulating compounds, including atrial-selective antiarrhythmic agents and ion channel modulating compounds that preferential ly modulate K+ channels. The ion channel modulating compounds identified according to these methods are associated with a reduced incidence of ventricular proarrhythmia.
申请公布号 CA2596983(A1) 申请公布日期 2009.02.10
申请号 CA20072596983 申请日期 2007.08.10
申请人 CARDIOME PHARMA CORP. 发明人 FEDIDA, DAVID
分类号 C12Q1/02;C07K14/705;C12N15/09 主分类号 C12Q1/02
代理机构 代理人
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