GASTRORETENTIVE SYSTEM CONTAINING SOLUBILIZED DRUG FOR MAXIMIZING ITS THERAPEUTIC EFFECT FOR GASTRITIS

摘要

There is provided a gastroretentive system matrix formulation containing a compound represented by Formula 1 that has a therapeutic effect on gastritis and is solubilized in the stomach, and a method for preparing the gastroretentive system matrix formulation. The gastroretentive system matrix formulation according to the present invention may be useful to improve the solubility of a solubilized drug under an acidic condition in the stomach, and maximize an anti-inflammatory effect of the solubilized drug by increasing the retention time of the formulation in the stomach through the continuous release the solubilized drug into the stomach.