发明名称 NOVEL ANTIBODIES INHIBITING C-MET DIMERIZATION, AND USES THEREOF
摘要 <p>The present inventions relates to a process for the selection of anti c-Met antibodies capable to inhibit both ligand-dependent and ligand-independent activation of c-Met. More particularly, said process is based on the inhibition of the c-Met dimerization. In another aspect, the present invention concerns such antibodies and compositions comprising such antibodies for the preparation of a medicament to treat cancer. Diagnosis process and kits are also part of the invention.</p>
申请公布号 CA2694418(A1) 申请公布日期 2009.01.15
申请号 CA20082694418 申请日期 2008.07.10
申请人 PIERRE FABRE MEDICAMENT 发明人 GOETSCH, LILIANE
分类号 C07K16/28;A61P35/00 主分类号 C07K16/28
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