发明名称 |
4-ARYL PIPERIDINES |
摘要 |
This invention is directed to 4-aryl piperidines and related heterocyclic compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. |
申请公布号 |
EA011029(B1) |
申请公布日期 |
2008.12.30 |
申请号 |
EA20060001315 |
申请日期 |
2005.01.13 |
申请人 |
H. LUNDBECK A/S |
发明人 |
MARZABADI MOHAMMAD, R.;WETZEL JOHN, M.;CHEN CHIEN-AN;DELEON JOHN, E.;JIANG YU;LU KAI |
分类号 |
A61K31/445;C07D211/26;C07D211/68;C07D401/04;C07D401/10;C07D401/14 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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