DISCRETE SIZE AND SHAPE SPECIFIC ORGANIC NANOPARTICLES DESIGNED TO ELICIT AN IMMUNE RESPONSE
摘要
The presently disclosed invention is broadly directed to therapeutic micro- and/or nanoparticles designed to target an immune cell with an active agent. More particularly, the particles have a predetermined geometry and a broadest dimension of less than about 10 µm. The immune cell-targeted micro and/or nanoparticles may additionally comprise a biocompatible polymer.
申请公布号
WO2008118861(A3)
申请公布日期
2008.12.18
申请号
WO2008US58022
申请日期
2008.03.24
申请人
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;DESIMONE, JOSEPH, M.;PETROS, ROBBY;FRELINGER, JEFFREY;BUNTZMAN, ADAM
发明人
DESIMONE, JOSEPH, M.;PETROS, ROBBY;FRELINGER, JEFFREY;BUNTZMAN, ADAM