摘要 |
Water-soluble salts of pharmaceutically acceptable bases with N-(2,4,6-triiodo-3-acylamino-5-carboxy-benzyl)-carbamic acid esters of the formula COOH ¦ R2-CO-NHCH2-NH-CO-OR1 n ARE RELATIVELY NON-TOXIC, QUICKLY EXCRETED X-ray contrast agents suitable for intravenous administration. The carboxylic acids of the formula are monoesters of alcohols R1OH having up to four carbon atoms which are alkanols, mono- and dihydroxyalkanols, or alkoxyalkanols, when n is 1, and diesters of alcohols HO-R1-R1OH having up to 10 carbon atoms which are alkanediols or ethyleneglycol ethers when n is 2. R2 has up to three carbon atoms and is alkyl, hydroxyalkyl, or alkoxyalkyl.
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