| 发明名称 |
PIPERIDINE DERIVATIVES AS NEUROKININ 1 ANTAGONISTS |
| 摘要 |
The invention relates to compounds of the general formula, wherein R1 is optionally substituted phenyl, morpholinyl, piperazinyl, pyrrolidinyl, piperidinyl or is thiomorpholinyl, 1-oxo-thiomorpholinyl or 1,1- dioxothiomorpholinyl. These compounds have a good affinity to the NK-1 receptor and they are therefore suitable in the control or treatment of diseases, related to this receptor. |
| 申请公布号 |
CA2435946(C) |
申请公布日期 |
2008.10.07 |
| 申请号 |
CA20022435946 |
申请日期 |
2002.01.28 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
SCHNIDER, PATRICK;KOLCZEWSKI, SABINE;ROEVER, STEPHAN |
| 分类号 |
C07D401/04;A61K31/451;A61K31/454;A61K31/4545;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61K31/541;A61P1/04;A61P1/08;A61P9/00;A61P11/00;A61P11/06;A61P11/08;A61P17/02;A61P19/02;A61P25/00;A61P25/02;A61P25/06;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/36;A61P27/02;A61P27/16;A61P29/00;A61P37/08;A61P43/00;C07D211/14;C07D211/16;C07D211/18;C07D211/26;C07D211/58;C07D295/12;C07D295/135;C07D401/12;C07D401/14;C07D413/04;C07D413/12;C07D413/14;C07D417/04 |
主分类号 |
C07D401/04 |
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