发明名称 PROCESS FOR PREPARING CLOPIDOGREL
摘要 The present invention discloses a process for the preparation of thieno[3,2-c]pyridine derivatives of general formula (I), in either racemic or optically active (+) or (-) forms and their salts, wherein X, the substituent on benzene ring represents either a hydrogen or halogen atom such as fluorine, chlorine, bromine or iodine. The present invention also describes a process for preparing the compounds of general formula (II), in either racemic or optically active (+) or (-) forms and their salts, where X, the substituent on benzene ring represents either a hydrogen or halogen atom such as fluorine, chlorine, bromine or iodine. The compounds represented by formulae (I) and (II) have one asymmetric carbon and hence, the optically active compounds of formula (I) or of formula (ii), may be obtained either by resolving the racemic intermediate/final product or using an optically active intermediate. The compounds of the invention are pharmacologically active and have significant anti-aggregating and anti-thrombotic properties.
申请公布号 EA006198(B2) 申请公布日期 2007.10.26
申请号 EA20030000831 申请日期 2002.01.21
申请人 CADILA HEALTHCARE LTD. 发明人 PANDEY BIPIN;LOHRAY VIDYA, BHUSHAN;LOHRAY BRAJ, BHUSHAN
分类号 A61K31/4365;A61P7/02;C07B55/00;C07B57/00;C07D495/04 主分类号 A61K31/4365
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