SUBSTITUTED WITH SULFAMIDES XANTINE DERIVATIVES FOR APPLICATION AS PHOSPHOENOLPYRUVATCARBOXYKINASE (PEPCK) INHIBITORS

摘要

FIELD: chemistry. ^ SUBSTANCE: substituted with sulfamides xantine derivaives of formula I or their pharmaceutically acceptable salts, where R1, R2 and R3 are such as given in invention description. Compounds of formula (I) and their pharmaceutically acceptable salts display activity as gluconeogenesis modulators and can be used for obtaining pharmaceutical compositions, which can be useful for treatment of type 2 diabetes. ^ EFFECT: increase of compound efficiency. ^ 35 cl, 98 ex, 1 tbl