<p>The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.</p>
申请公布号
EP1996184(A2)
申请公布日期
2008.12.03
申请号
EP20070759058
申请日期
2007.03.21
申请人
JOYANT PHARMACEUTICALS, INC.
发明人
HANSON, GUNNAR, J.;THOMAS, DAVID;CHANDRAKIMAR, NIZAL;HARRAN, SUSAN