| 发明名称 |
High purity peptides |
| 摘要 |
The invention relates to methods for the preparation of highly purified peptides. The peptides are prepared in high optical purity of at least about 98.5%, and preferably at least about 99%. Specifically, Nesiritide (SEQ. ID NO. 1) having a purity of at least 99% as measured by HPLC and containing about 0.05% to about 0.5% [D-His]-Nesiritide (SEQ. ID NO. 1) as measured by chiral GC/MS.
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| 申请公布号 |
US2008287650(A1) |
申请公布日期 |
2008.11.20 |
| 申请号 |
US20080074454 |
申请日期 |
2008.03.03 |
| 申请人 |
TOVI AVI;EIDELMAN CHAIM;SHUSHAN SHIMON;ELSTER SHAI;HAGI ALON;IVCHENKO ALEXANDER;BUTILCA GABRIEL-MARCUS;ZAOUI GIL;ALTERMAN ELEONORA;BAR-OZ LEAH |
发明人 |
TOVI AVI;EIDELMAN CHAIM;SHUSHAN SHIMON;ELSTER SHAI;HAGI ALON;IVCHENKO ALEXANDER;BUTILCA GABRIEL-MARCUS;ZAOUI GIL;ALTERMAN ELEONORA;BAR-OZ LEAH |
| 分类号 |
C07K1/00;C07K1/04;C07K7/08;C07K7/64;C07K14/00 |
主分类号 |
C07K1/00 |
| 代理机构 |
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