发明名称 METHOD OF MANUFACTURING OF VACCINE ASSOCIATED AGAINST COLIBACILLOSIS, SALMONELLOSIS AND ENTEROCOCCUS INFECTIONS OF NUTRIAS
摘要 FIELD: medicine; pharmacology. ^ SUBSTANCE: essence of the invention includes selection of the damaged organs from the dead nutrias from the local epidemical centre from which prepare suspension, perform bacterial inoculation in differenrial diagnostic mediums, separate pure cultures of originators of colibacillosis, salmonellosis and enterococcus infections, separately grow up cultures Escherichia coli. Salmonella typhimurium and Streptococcus, fecalis in a meat infusion agar with addition of 0.2% of a glucose with titer 4-5 billion microbic cells in 1 cm3, inactivate by entering of formalin to 0.4-0.6 % final concentration, condition at temperature 37°C within 72-96 hours, admix cultures in equal parities, then bring a solution of a aluminium hydroxide in amount of 20% to the volume, carefully admix, pack up and cork. ^ EFFECT: increase of an adjuvanticity of a vaccine. ^ 1 tbl
申请公布号 RU2338554(C2) 申请公布日期 2008.11.20
申请号 RU20060102759 申请日期 2006.01.31
申请人 FEDERAL'NOE GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "KUBANSKIJ GOSUDARSTVENNYJ AGRARNYJ UNIVERSITET" 发明人 SHEVCHENKO LJUDMILA VASIL'EVNA;SHEVCHENKO ALEKSANDR ALEKSEEVICH;SHEVCHENKO ANNA ALEKSANDROVNA;FABRIKANTOVA OL'GA VALER'EVNA
分类号 A61K39/116;A61P31/04 主分类号 A61K39/116
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