摘要 |
The invention provides the use of a compound selected from compounds of the formula (2) and pharmaceutically acceptable salts thereof in which: R1 is halogen; either R2 is H and R3 is XR4 or R3 is H and R2 is XR4; X is -COCH=CH- or -CH=CHCO-; and XR4 is Formula (I) in which: R5, R6, R7, and R8 are independently H, halogen, OR9 or CH2- NR10R11 in which R9 is H or C<SUB>1</SUB>-C<SUB>3</SUB> alkyl and R10 and R11 are together or independently H, pyrrolidinyl, piperidinyl, morpholinyl, -CH<SUB>2</SUB> - morpholine, 1 -ethyl-1 -piperizinyl, t- butylamino, dimethylamino or diethylamino, in the manufacture of a medicament for the inhibition of the growth of tumour cells. |
申请人 |
UNIVERSITY OF PRETORIA;MEDLEN, CONSTANCE, ELIZABETH;CHIBALE, KELLY;SOARES DE MELO, CANDICE |
发明人 |
MEDLEN, CONSTANCE, ELIZABETH;CHIBALE, KELLY;SOARES DE MELO, CANDICE |