| 摘要 |
The present invention is directed to methods, computer software and assay kits to identify epitopes, such as HLA epitopes. The preferred method comprises steps of constructing data tables of possible polymorphic sites of epitopes defined by a single antigen product, such as single antigen beads and, for a given string of specificities, searching the data table and presenting a list of possible single residues to explain the reactions. The methods, assay kits and computer software disclosed herein may also include an option for users to specify which positions or which paired positions to exclude and other parameters may be used to reduce the number of possible epitopes. In addition a graphical interface, such as a three-dimensional graph, may be included to permit easier selection from the multiple possibilities. |
