COMPOSITION COMPRISING S-ALLYLMERCAPTO-N-ACETYLCYSTEINE (ASSNAC) FOR UP-REGULATION OF CELLULAR GLUTATHIONE LEVEL
摘要
<p>The present invention relates to S-allylmercapto-N-acetylcysteine (ASSNAC) and its pharmaceutically acceptable salts and solvates, which are useful for up-regulation of cellular glutathione levels and expression of phase II detoxifying enzymes. The invention further provides methods of use thereof in the prevention, alleviation or treatment of oxidative stress induced by reactive oxygen species (ROS).</p>
申请公布号
WO2008135984(A1)
申请公布日期
2008.11.13
申请号
WO2008IL00600
申请日期
2008.05.01
申请人
RAMOT AT TEL-AVIV UNIVERSITY LTD.;YEDA RESEARCH AND DEVELOPMENT CO. LTD.;SAVION, NAPHTALI;MIRELMAN, DAVID;RABINKOV, AHARON;KHENKIN, ALEX
发明人
SAVION, NAPHTALI;MIRELMAN, DAVID;RABINKOV, AHARON;KHENKIN, ALEX