发明名称 NOVEL PYRIMIDINE COMPOUND HAVING DIBENZYLAMINE STRUCTURE, AND MEDICINE COMPRISING THE COMPOUND
摘要 <p>This invention provides a compound represented by general formula (I) having a high level of inhibitory activity against a cholesterol ester transfer protein (CETP) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, and R<SUP>5</SUP> represent a hydrogen atom, a halo-lower alkyl group, a cyano group or the like; R<SUP>6</SUP> represents an alkyl group, a cycloalkyl group or the like; R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>9</SUP>, and R<SUP>10</SUP> represent a hydrogen atom, a halogen atom, a lower alkyl group, a halo-lower alkyl group or the like; R<SUP>11</SUP> and R<SUP>12</SUP> represent a hydrogen atom, a lower alkyl group, a lower cycloalkyl lower alkyl group or the like; and R<SUP>13</SUP> represents a hydrogen atom, a halogen atom, a lower alkoxy group or the like.</p>
申请公布号 WO2008129951(A1) 申请公布日期 2008.10.30
申请号 WO2008JP57058 申请日期 2008.04.10
申请人 KOWA COMPANY, LTD.;OHGIYA, TADAAKI;MIURA, TORU;OKUDA, AYUMU;ARAI, TOSHIHARU;YAMAZAKI, KOICHI;AOKI, TARO;MIYOSAWA, KATSUTOSHI;SHIBATA, HARUKI;SHIBUYA, KIMIYUKI 发明人 OHGIYA, TADAAKI;MIURA, TORU;OKUDA, AYUMU;ARAI, TOSHIHARU;YAMAZAKI, KOICHI;AOKI, TARO;MIYOSAWA, KATSUTOSHI;SHIBATA, HARUKI;SHIBUYA, KIMIYUKI
分类号 C07D239/42;A61K31/505;A61P3/06;A61P7/02;A61P9/00;A61P43/00;C07D403/12 主分类号 C07D239/42
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