NOVEL 5-CYANO-PROSTACYCLIN DERIVATIVES AND THEIR USE AS AGENTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES

摘要

This invention is directed to compounds of formula (I): where A, B, D, E, m, and R<SUP>1</SUP> - R<SUP>5</SUP> are as described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, clathrates, or prodrugs thereof, which compounds are useful in treating autoimmune diseases. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.