| 发明名称 |
Heterodimeric protein binding compositions |
| 摘要 |
The invention relates to methods for making modified immunoglobulin compositions to maximize antigen binding and effector function by swapping of sequences of the heavy and light chains within an IgG Fab domain for the purpose of reorienting the Fc domain relative to the antigen-binding domain. |
| 申请公布号 |
AU2006218876(A1) |
申请公布日期 |
2006.09.08 |
| 申请号 |
AU20060218876 |
申请日期 |
2006.02.24 |
| 申请人 |
CENTOCOR, INC. |
发明人 |
BERNARD SCALLON |
| 分类号 |
C07K16/00;A61K39/395;C07H21/04;C07K17/00;C12N5/06;C12N15/00;C12P21/06;C12Q1/68 |
主分类号 |
C07K16/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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