发明名称 NOVEL BISBORON COMPOUND
摘要 <p>A bisboron compound represented by the general formula (I): wherein B represents a boron atom, Y represents an oxygen or sulfur atom, R 1 and R 2 independently represent a monocyclic aromatic group, a polycyclic aromatic group, or a heterocyclic group containing at least one heteroatom selected from oxygen, nitrogen and sulfur atoms, R 3 represents a hydrogen atom; -(CH 2 ) m -NR 4 R 5 ; -CO-(CH 2 ) m -NR 4 R 5 ; - COCH(NH 2 )R 6 ; -CHR 7 R 8 ; -CH 2 CH(NH 2 )-R 9 ; quinolyl substituted with C1-C4 alkyl group; or C1-C4 alkyl substituted with pyridyl, piperidino or pyrrolidinyl group, and X represents a monocyclic atomatic group, a polycyclic aromatic group or a heterocyclic group, which may be the same as or different from R 1 and R 2 , or a bifunctional group having a monocyclic aromatic group, polycyclic aromatic group or heterocyclic group bonded to each side of a group selected from the group consisting of a single bond, O, CH 2 , S, SO 2 , CH 2 OCH 2 , OCH 2 , OCH 2 CH 2 OCH 2 , OCH 2 OCH 2 CH 2 and CH 2 OCH 2 CH 2 , or a salt thereof, and a composition for controlling the intracellular calcium concentration, which comprises the compound or salt thereof as an active ingredient.</p>
申请公布号 EP1961756(A1) 申请公布日期 2008.08.27
申请号 EP20060833296 申请日期 2006.11.24
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 MIKOSHIBA, KATSUHIKO;OZAKI, SHOICHIRO;SUZUKI, AKINOBU;NAKAMURA, TAKESHI
分类号 C07F5/02;A61K31/69;A61P1/18;A61P9/10;A61P9/12;A61P11/06;A61P13/12;A61P25/28;A61P37/02;A61P37/08;A61P43/00 主分类号 C07F5/02
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