发明名称 Process for production of 2-chloro-4-nitroimidazole
摘要 The present invention provides a process for production of 2-chloro-4-nitroimidazole in a high yield and at a high purity by a simple operation in a safer manner involving a low risk of explosion or the like. The present invention provides a process for production of 2-chloro-4-nitroimidazole represented by the formula (1): comprising a reaction of a 1-alkoxyalkyl-2-bromo-4-nitroimidazole compound represented by the general formula (7): wherein R1 represents a lower alkyl group, and n represents an integer of 1 to 3, with hydrogen chloride.
申请公布号 ZA200702426(B) 申请公布日期 2008.08.27
申请号 ZA20070002426 申请日期 2005.09.27
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 SHINHAMA, KOICHI
分类号 A61K;C07D 主分类号 A61K
代理机构 代理人
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