发明名称 |
METHOD OF PROBIOTIC PREPARATIONS OBTAINING AND CONTROL |
摘要 |
FIELD: microbiology. ^ SUBSTANCE: invention can be applied in production of probiotic preparations based on lacto- and bifidobacteria. The method involves consequent triple bacteria seeding to a nutrient medium to obtain stock culture, reactive accumulation of bacteria biomass and defining biological parametres of the preparadion obtained. Nutrient medium is a caseic yeast medium containing 20-25% of yeast autolysate and 10-15% of caseic hydrolysate. To obtain stock culture for bacteria the 1st and 3rd seeding to caseic yeast medium is alternated with seeding to another nutrient medium, MPC-1 for lactobacteria and modified liver medium for bifidobacteria. ^ EFFECT: reduced cost, nutrition media unification at the stages of preparations production and control, reduced by - products consumption for caseic yeast medium preparation. |
申请公布号 |
RU2332454(C2) |
申请公布日期 |
2008.08.27 |
申请号 |
RU20060121988 |
申请日期 |
2006.06.21 |
申请人 |
FEDERAL'NOE GOSUDARSTVENNOE UNITARNOE PREDPRIJATIE "NAUCHNO-PROIZVODSTVENNOE OB"EDINENIE PO MEDITSINSKIM IMMUNOBIOLOGICHESKIM PREPARATAM "MIKROGEN" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII |
发明人 |
NESCHISLJAEV VALERIJ ALEKSANDROVICH;SKUDAEVA LJUDMILA KLAVDIEVNA;PAVLENKO IRINA VASIL'EVNA;BASHKIRTSEVA NATAL'JA LEONIDOVNA |
分类号 |
C12N1/20;A61K35/74 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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地址 |
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