发明名称 METHOD OF PROBIOTIC PREPARATIONS OBTAINING AND CONTROL
摘要 FIELD: microbiology. ^ SUBSTANCE: invention can be applied in production of probiotic preparations based on lacto- and bifidobacteria. The method involves consequent triple bacteria seeding to a nutrient medium to obtain stock culture, reactive accumulation of bacteria biomass and defining biological parametres of the preparadion obtained. Nutrient medium is a caseic yeast medium containing 20-25% of yeast autolysate and 10-15% of caseic hydrolysate. To obtain stock culture for bacteria the 1st and 3rd seeding to caseic yeast medium is alternated with seeding to another nutrient medium, MPC-1 for lactobacteria and modified liver medium for bifidobacteria. ^ EFFECT: reduced cost, nutrition media unification at the stages of preparations production and control, reduced by - products consumption for caseic yeast medium preparation.
申请公布号 RU2332454(C2) 申请公布日期 2008.08.27
申请号 RU20060121988 申请日期 2006.06.21
申请人 FEDERAL'NOE GOSUDARSTVENNOE UNITARNOE PREDPRIJATIE "NAUCHNO-PROIZVODSTVENNOE OB"EDINENIE PO MEDITSINSKIM IMMUNOBIOLOGICHESKIM PREPARATAM "MIKROGEN" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII 发明人 NESCHISLJAEV VALERIJ ALEKSANDROVICH;SKUDAEVA LJUDMILA KLAVDIEVNA;PAVLENKO IRINA VASIL'EVNA;BASHKIRTSEVA NATAL'JA LEONIDOVNA
分类号 C12N1/20;A61K35/74 主分类号 C12N1/20
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