摘要 |
The invention relates to compounds of formula (I) wherein R<SUP>1</SUP> is aryl or heteroaryl, wherein the aryl and heteroaryl groups may be unsubstituted or substituted by one to three substituents, selected from the group consisting of cycloalkyl, phenyl, phenyloxy, benzyl, benzyloxy, halogen, lower alkyl, lower alkoxy, heteroaryl, piperidin-1-yl or by lower alkyl substituted by halogen, or is aryl or heteroaryl wherein at least one hydrogen atom is replaced by deuterium or tritium; R<SUP>2</SUP> is hydrogen, lower alkyl or is benzyl unsubstituted or substituted by alkoxy or halogen; or R<SUP>1</SUP> and R<SUP>2</SUP> form together with the N-atom to which they are attached 2,3-dihydroindol-1-yl or 3,4-dihydro-quinolin-1-yl; R<SUP>3</SUP> is hydrogen or lower alkyl or to a pharmaceutically suitable acid addition salt thereof for the treatment of CNS disorders. |
申请人 |
F. HOFFMANN-LA ROCHE AG;GALLEY, GUIDO;GROEBKE ZBINDEN, KATRIN;NORCROSS, ROGER;STALDER, HENRI |
发明人 |
GALLEY, GUIDO;GROEBKE ZBINDEN, KATRIN;NORCROSS, ROGER;STALDER, HENRI |