| 发明名称 |
SYNTHESIS OF 1A-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL |
| 摘要 |
The invention provides a method of producing 20-methyl vitamin D3 compoun ds of formula (I). The method includes hydroxylation, carbonyl reduction, fl uoride substitution, epoxide deoxygenation, and Wittig-type couplings.
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| 申请公布号 |
CA2676512(A1) |
申请公布日期 |
2008.07.31 |
| 申请号 |
CA20082676512 |
申请日期 |
2008.01.25 |
| 申请人 |
BIOXELL S.P.A. |
发明人 |
MAEHR, HUBERT;USKOKOVIC, MILAN R. |
| 分类号 |
A61K31/59;C07C401/00;C07C403/00 |
主分类号 |
A61K31/59 |
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