| 发明名称 |
Receptor-based interaction trap |
| 摘要 |
<p>The present invention relates to a recombinant receptor, comprising an extracellular ligand-binding domain and a cytoplasmic domain that comprises a heterologous bait polypeptide, which receptor is activated by binding of a ligand to said ligand binding domain and by binding of a prey polypeptide to said heterologous bait peptide. The present invention also relates to a method to detect compound-compound binding using said recombinant receptor.</p> |
| 申请公布号 |
EP1612221(A3) |
申请公布日期 |
2008.07.23 |
| 申请号 |
EP20050016201 |
申请日期 |
2001.05.22 |
| 申请人 |
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW. |
发明人 |
EYCKERMAN, SVEN;VAN OSTADE, XAVEER;VANDEKERCKHOVE, JOEL;VANHEE, ANNICK;TAVERNIER, JAN |
| 分类号 |
C12N15/10;G01N33/53;C07K14/00;C07K14/71;C07K14/715;C12N1/15;C12N1/19;C12N5/10;C12N15/09;C12N15/62;C12Q1/02;C12Q1/68;G01N33/566 |
主分类号 |
C12N15/10 |
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