| 发明名称 |
PI-3 kinase inhibitor prodrugs |
| 摘要 |
The invention provides prodrugs of inhibitors of PI-3 kinase. The compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.
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| 申请公布号 |
US7396828(B2) |
申请公布日期 |
2008.07.08 |
| 申请号 |
US20050111201 |
申请日期 |
2005.04.20 |
| 申请人 |
SEMAFORE PHARMACEUTICALS, INC. |
发明人 |
GARLICH JOSEPH R.;DURDEN DONALD L.;PATTERSON MARY;SU JINGDONG;SUHR ROBERT G. |
| 分类号 |
A61K31/33;A61K31/35;A61K31/353;A61K31/40;A61K31/415;A61K31/47;A61K31/535;A61P25/00;C07C381/00;C07D207/40;C07D207/404;C07D257/02;C07D311/22;C07D311/76;C07D405/04;C07D405/12;C07D407/12;C07D413/04;C07D475/04 |
主分类号 |
A61K31/33 |
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