| 摘要 |
The present invention relates to compounds of formula (I):wherein:• X and Y represent a hydrogen atom;• Z represents an oxygen atom;• Ar represents an aryl group,• Rrepresents a linear or branched C-C-alkyl group;• Rrepresents -ORa wherein Rrepresents a linear or branched C-C-alkyl group;• Rand Rrepresent a linear or branched C-C-alkyl group;• Rrepresents a group selected fromOR, W-C(W)-U-V, wherein α) Wrepresents an oxygen atom, &bgr;) Wrepresents an oxygen atom, γ) U represents single bond or linear or branched C-C-alkylene or linear or branched C-C-alkenylene chain, δ) V represents a group selected from a hydrogen atom, an aryl group, as well as to their enantiomers, diastereoisomers, also addition salts thereof with a pharmaceutically acceptable acid or base and to hydrates and solvates. The invention also relates to pharmaceutical compositions containing a compound of formula (I) as an active component especially useful as a medicament in the treatment of cancers. |
