发明名称 INDANYL-PIPERAZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 Compound of formula (I):wherein:Rrepresents a hydrogen atom, and Rand Rtogether with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted by one or more identical or different substituents selected from hydrogen, halogen and linear or branched C-Calkyl optionally substituted by one or more halogen atoms,or Rrepresents a hydrogen atom, and Rand Rtogether with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted by one or more identical or different substituents selected from hydrogen, halogen and linear or branched C-Calkyl optionally substituted by one or more halogen atoms,n represents 1 or 2,-X- represents a group selected from -(CH)-O-Ak-, -(CH)-NR-Ak-, -(CO)-NR-Ak- and -(CH)-NR-(CO)-,m represents an integer between 1 and 6 inclusive, Ak represents an optionally substituted alkylene chain, and Rrepresents a hydrogen atom, or alkyl group,Ar represents aryl or heteroaryl group,and its enantiomers, diasteroisomers, and addition salts thereof with a pharmaceutically acceptable acid.Medicaments.
申请公布号 EA010051(B1) 申请公布日期 2008.06.30
申请号 EA20060000487 申请日期 2006.03.29
申请人 LES LABORATOIRES SERVIER 发明人 DE-NANTEUIL GUILLAUME;PORTEVIN BERNARD;GLOANEC PHILIPPE;MILLAN MARK;ORTUNO JEAN-CLAUDE;MANNOURY-LA-COUR CLOTILDE;GOBER ALAIN
分类号 C07D295/033;A61K31/495;A61K31/496;A61P25/00;C07D213/56;C07D333/38 主分类号 C07D295/033
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