ПО СУЩЕСТВУ ЧИСТАЯ 2-{[2-(2-МЕТИЛАМИНОПИРИМИДИН-4-ИЛ)-1Н-ИНДОЛ-5-КАРБОНИЛ]-АМИНО}-3-(ФЕНИЛПИРИДИН-2-ИЛАМИНО)-ПРОПИОНОВАЯ КИСЛОТА В КАЧЕСТВЕ ИНГИБИТОРА 1КВ КИНАЗЫ

摘要

The present invention is directed to the substantially pure compound of formula (A), or pharmaceutically acceptable salt, or solvate of said compound; to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula (A), and a pharmaceutically acceptable carrier; and the use of a compound of formula (A) having activity as an inhibitor, preferably a selective inhibitor, of IkB (IKK), particularly IKK-2, and methods related thereto.