BACTERIAL DELIVERY OF BIOLOGICALLY ACTIVE POLYPEPTIDES
摘要
The present invention relates to methods for the delivery of biologically active polypeptides to a subject by colonizing non-pathogenic Gram negative bacteria. Also provided by this invention are methods of treating or preventing diseases by administering colonizing Gram negative bacteria that express one or more biologically active polypeptides. The colonizing non-pathogenic Gram negative bacteria may be administered in pharmaceutical formulations.
申请公布号
EP1934349(A1)
申请公布日期
2008.06.25
申请号
EP20060774884
申请日期
2006.08.29
申请人
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
发明人
MOORE, ROBERT, JOHN;ROOD, JULIAN, IAN;SHEEDY, SCOTT, ANDREW