发明名称 Chemically cleavable 3'-0-allyl-dntp-allyl-fluorophore fluorescent nucleotide analogues and related methods
摘要 This invention provides a nucleotide analog comprising (i) a base selected from the group consisting of adenine, guanine, cytosine, thymine and uracil, (ii) a deoxyribose, (iii) an allyl moiety bound to the 3′-oxygen of the deoxyribose and (iv) a fluorophore bound to the base via an allyl linker, and methods of nucleic acid sequencing employing the nucleotide analog.
申请公布号 GB0808033(D0) 申请公布日期 2008.06.11
申请号 GB20080008033 申请日期 2006.10.31
申请人 TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE 发明人
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