发明名称 |
INDOLE DERIVATIVES and their application for the preparation of drugs |
摘要 |
Indole derivatives of formula I, their salts and solvates, have valuable pharmacological properties together with good tolerability, as they have actions on the central nervous system:wherein R<1 >and R<3 >are as defined herein. The compounds have a strong affinity for 5-HT2A receptors, and furthermore exhibit 5HT2A receptor-antagonistic properties. These are therefore suitable both in veterinary and in human medicine for the treatment of functional disorders of the central nervous system and also of inflammation. |
申请公布号 |
PL197847(B1) |
申请公布日期 |
2008.05.30 |
申请号 |
PL20000354971 |
申请日期 |
2000.07.07 |
申请人 |
MERCK PATENT GMBH |
发明人 |
BOETTCHER HENNING;MARZ JOACHIM;GREINER HARTMUT;HARTING JUERGEN;BARTOSZYK GERD;SEYFRIED CHRISTOPH;VAN AMSTERDAM CHRISTOPH |
分类号 |
A61K31/496;C07D403/06;A61K31/404;A61P15/00;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P43/00;C07D209/12;C07D209/42;C07D405/14;C07D409/14 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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