CRYSTAL FORMS OF 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL AND PHARMACEUTICAL FORMULATIONS THEREOF

摘要

The present invention is directed to crystal forms (Forms B, D, E, and F described herein) of 2-(3-fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol, an estrogenic receptor modulator useful in the treatment of, for example, diseases related to abnormal levels of estrogen. The present invention is also directed to pharmaceutical formulations and compositions of the crystal forms (Form B, D, E and F described herein) of the estrogen receptor modulator, and processes for their preparation.