发明名称 |
PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF |
摘要 |
<p>PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF A probucol or a probucol derivative can be efficiently converted to a monoester or monoether of probucol by reacting the free hydroxyl-containing probucol or a derivative thereof (by which is meant a probucol compound with at least one substituent that is different from that on the parent probucol molecule but which maintains the two free hydroxyl groups) with a Grignard reagent or a lithium reagent that produces a magnesium bromide or lithium salt of probucol or the probucol derivative. The probucol compound anion anion is then reacted with an ester or ether forming compound.</p> |
申请公布号 |
SG142207(A1) |
申请公布日期 |
2008.05.28 |
申请号 |
SG20070051279 |
申请日期 |
2004.01.13 |
申请人 |
ATHEROGENICS, INC. |
发明人 |
WEINGARTEN, M. DAVID;SIKORSKI, JAMES A. |
分类号 |
C07C319/20;C07C323/20 |
主分类号 |
C07C319/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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