摘要 |
A method of generating a platelet reactivity profile of an individual com prises the steps of providing a platelet- containing biological sample from the individual, providing at least three platelet function modulators, each platelet function modulator being provided in at least three concentrations, and reacting an aliquot of the platelet containing sample with each concent ration of each platelet function modulator in a separate reaction vessel. Pl atelet aggregation is then measured in each reaction vessel, and the platele t aggregation measurements are used to generate a dose response curve for ea ch platelet function modulator, wherein the dose response curves obtained an d/or one or more functions of the dose response curves obtained, comprise a platelet reactivity profile for the individual. Clinical applications of, an d kits for carrying out, the methods of the invention are also described.</S DOAB>
|