| 摘要 |
<p>The invention relates to compounds having general formula (I), wherein R represents a group that is selected from pyrazolyl, imidazolyl, triazolyl, oxazolyl, oxadiazolyl, thiazolyl, isothiazolyl, thiadiazolyl, tetrazolyl, said group being optionally substituted by one or more groups selected from among halogen atoms, groups (C<sub>1</sub>-C<sub>6</sub>)alkyl, (C<sub>1</sub>-C<sub>6</sub>)alkoxy, trifluoromethoxy, trifluoromethyl, nitro, cyano, hydroxy, amino, (C<sub>1</sub>-C<sub>6</sub>)alkylamino or di(C<sub>1</sub>-C<sub>6</sub>)alkylamino, with a single or double carbon-carbon bond between positions 3 and 4 of the azabicyclooctane ring; in the form of a base, an acid addition salt, a hydrate or a solvate. The invention also relates to the method of preparing said compounds and to the use of same in therapeutics.</p> |
